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JoVE Journal
Behavior

This content is Open Access.

JoVE Journal Behavior
Rodent Brain Microinjection to Study Molecular Substrates of Motivated Behavior
 

Rodent Brain Microinjection to Study Molecular Substrates of Motivated Behavior

Article doi: 10.3791/53018
September 16th, 2015 •
1, 1, 1, 1,2
1Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University School of Medicine, 2Institute for Drug and Alcohol Studies, Departments of Psychiatry, Pharmacology, and Neuroscience, Virginia Commonwealth University School of Medicine

Summary
Automatic Translation
September 16th, 2015

Rodents are an appropriate model to investigate the molecular substrates of behavior and complex psychiatric disorders. Brain microinjection in awake rodents can be used to elucidate disease substrates. An efficient and customizable brain microinjection method as well as the execution of an operant paradigm that quantifies motivation is presented.

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