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A Step by Step Protocol for Subretinal Surgery in Rabbits

A Step by Step Protocol for Subretinal Surgery in Rabbits

Article DOI: 10.3791/53927-v 12:31 min September 13th, 2016
September 13th, 2016



Retinal pigment epithelium (RPE) replacement strategies and gene-based therapy are considered for several retinal degenerative conditions. For clinical translation, large eye animal models are required to study surgical techniques applicable in patients. Here we present a rabbit model for subretinal surgery geared towards RPE transplantation, which is versatile and cost-efficient.


Subretinal Surgery Rabbits RPE-related Diseases Age-related Macular Degeneration Cell-based Therapy Optometric Field Transport Modality Drug-delivery Devices Vitrectomy Model Organisms Pigs Monkeys Humans Intraocular Surgery Anesthesia Eye Ointment Surgical Microscope Disinfect Povidone Iodine
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