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Co-kultur av levnads- Microbiome med Microengineered Human Intestinal Villi i en Gut-on-a-chip mikroflödessystem enhet
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device
DOI:

10:51 min

August 30, 2016

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Chapters

  • 00:05Title
  • 01:24Growth of Microengineered Intestinal Villi in the Gut-on-a-Chip Device
  • 03:45Formation of Microengineered Caco-2 Villi in the Gut-on-a-Chip
  • 05:55Application of Mechanical Deformations Mimicking Peristalsis-like Motions
  • 06:37Host-gut Microbiome Co-culture in a Gut-on-a-chip Microdevice
  • 09:07Results: Emulating the Human Intestinal Host-microbiome Ecosystem
  • 09:44Conclusion

Summary

Automatic Translation

Vi beskriver en in vitro-protokoll för att co-kultur gut microbiome och intestinal villi under en längre tid med användning av en human gut-on-a-chip microphysiological systemet.

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