Два методы, чтобы создать Hypoparathyroid Мыши: паратиреоидэктомию Использование GFP железах и дифтерийно-Токсин-опосредованной паратиреоидного абляции
Mice with acquired hypoparathyroidism would be useful for studying novel drug therapies for hypoparathyroidism. Two procedures to create such mice are demonstrated. The GFP-PTX mouse is generated by surgical parathyroidectomy guided by green fluorescing parathyroid glands. A second, non-surgical approach is based on parathyroid-specific expression of the diphtheria toxin receptor.