Visualisatie van eiwit-eiwit interacties in nucleaire en cytoplasmatische fracties door Co-immunoprecipitatie en<em> In Situ</em> Proximity Ligatie Assay
Protein-protein interactions can occur in both the nucleus and the cytoplasm of a cell. To investigate these interactions, traditional co-immunoprecipitation and modern proximity ligation assay are applied. In this study, we compare these two methods to visualize the distribution of NF90-RBM3 interactions in the nucleus and the cytoplasm.