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超声引导下人骨髓间充质干细胞在实验性肠炎小鼠模型中的应用
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JoVE Journal Medicine
Ultrasound-guided Intracardiac Injection of Human Mesenchymal Stem Cells to Increase Homing to the Intestine for Use in Murine Models of Experimental Inflammatory Bowel Diseases
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超声引导下人骨髓间充质干细胞在实验性肠炎小鼠模型中的应用

DOI:
10.3791/55367-v

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07:45 min

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September 01, 2017

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, , , , , , ,
1Division of Gastroenterology and Liver Disease, University Hospitals, Digestive Health Research Institute,Case Western Reserve University, 2Case Cardiovascular Research Institute, School of Medicine,Case Western Reserve University, 3Department of Medicine, Harrington Discovery Institute, Harrington Heart and Vascular Institute,University Hospitals Case Medical Center, 4Department of Radiology,University Hospitals Case Medical Center, 5Department of Biology – Skeletal Research Center,Case Western Reserve University

Chapters

  • 00:05Title
  • 01:09Ultrasound-guided Intracardiac Human Mesenchymal Stem Injection
  • 03:59hMSC Bioluminescent (BLI) Imaging
  • 05:31Results: Representative In Vivo hMSC Visualization
  • 06:13Conclusion

Summary

Automatic Translation

Automatic Translation

小鼠在结肠炎症模型中的研究表明, 一小部分 (1-5%) 的间充质干细胞 (MSC) 静脉注射或腹腔回家到发炎的结肠1,2。本研究表明, 超声引导下的骨髓间充质干细胞注射可增加肠道定位。

Tags

Ultrasound-guidedIntracardiac InjectionHuman Mesenchymal Stem CellsHomingInflammatory Bowel DiseasesCrohn’s DiseaseMouse ModelCell SuspensionSyringeNeedleEchocardiogramSedationDepilatory CreamDisinfectionUltrasound GelLeft Ventricle

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