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Ultralyd-guidede Intracardiac injeksjon for menneskelige stamceller å øke Homing til tarmen for bruk i Murine modeller av eksperimentelle inflammatorisk tarm sykdommer
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Ultralyd-guidede Intracardiac injeksjon for menneskelige stamceller å øke Homing til tarmen for bruk i Murine modeller av eksperimentelle inflammatorisk tarm sykdommer

Article DOI: 10.3791/55367 • 07:46 min • September 1st, 2017
September 1st, 2017 •
1, 1, 2,3, 5, 4, 2,3, 5, 1
1Division of Gastroenterology and Liver Disease, University Hospitals, Digestive Health Research Institute, Case Western Reserve University, 2Case Cardiovascular Research Institute, School of Medicine, Case Western Reserve University, 3Department of Medicine, Harrington Discovery Institute, Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, 4Department of Radiology, University Hospitals Case Medical Center, 5Department of Biology - Skeletal Research Center, Case Western Reserve University

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Murine studier i modeller av colonic betennelse har vist at en liten prosentandel (1-5%) av mesenchymal stamceller (MSC) injiseres intravenøst eller intraperitoneally hjem til betent kolon1,2. Denne studien viser at ultralyd-guidede intracardiac injeksjoner av MSCs resultere i økt lokalisering til tarmen.

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Medisin problemet 127 Mesenchymal stamceller (MSC) Crohns sykdom SAMP1/YitFc ultralyd-guidede intracardiac injeksjon hMSC transduction bioluminescens bildebehandling
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