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Chapters
- 00:05Title
- 00:37Preparation of Amino Acid Solutions
- 01:16Preparation of SAP-AA Solutions
- 01:56Preparation of Drug-DMSO or Drug-Ethanol Stock Solutions and Drug Formulations
- 03:11Solubility Testing
- 03:36Results: Enhancement of Hydrophobic Compound Solubility in Aqueous Solution with Self-assembling Peptide and Amino Acid Solutions
- 04:16Conclusion
Denne protokol beskriver en klinisk relevant middel til at opløse hydrofobe forbindelser i et vandigt miljø ved hjælp af kombinationer af selvstændige montering peptid og aminosyre løsninger. Vores metode løser en stor begrænsning af hydrofobe therapeutics, der mangler sikker, effektiv middel til opløselighed og levering metoder til kliniske indstillinger.
