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Metodologi for biomimetiske kemiske Neuromodulationsbehandling af rotte nethinder med neurotransmitteren glutamat In Vitro
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Chapters
- 00:05Title
- 01:16Wholemount Retinal Preparation
- 03:12MEA and Data Acquisition Setup
- 05:23Glutamate Stimulation Preparation
- 08:38Retinal Recording and Stimulus Program
- 10:30Results: Electrode Recordings of Neuronal Activity During Visual, Spontaneous, and Glutamate Injection Recordings
- 12:06Conclusion
Denne protokol beskriver en roman metode for at undersøge en form for kemisk neurostimulation wholemount rotte nethinder i vitro med neurotransmitteren glutamat. Kemiske neurostimulation er en lovende alternativ til den konventionelle elektrisk neurostimulation retinal neuroner til behandling af uoprettelige blindhed forårsaget af fotoreceptor degenerative sygdomme.
