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Behavior
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一种诱导大鼠抑郁症状行为的新方法
JoVE Journal
Behavior
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JoVE Journal
Behavior
A New Method for Inducing a Depression-Like Behavior in Rats
Please note that all translations are automatically generated.
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一种诱导大鼠抑郁症状行为的新方法
DOI:
10.3791/57137-v
•
07:57 min
•
February 22, 2018
•
Vladimir Zeldetz*
1
,
Dmitry Natanel*
2
,
Matthew Boyko
,
Alexander Zlotnik
,
Honore N. Shiyntum
,
Julia Grinshpun
,
Dmitry Frank
,
Ruslan Kuts
,
Evgeni Brotfain
,
Jochanan Peiser
1
Department of Emergent Medicine, Soroka University Medical Center
,
Ben-Gurion University of the Negev
,
2
Division of Anesthesiology and Critical Care, Soroka Medical Center
,
Ben-Gurion University of the Negev
,
3
Department of Biophysics and Biochemistry
,
Oles’ Honchar Dnipro National University
Chapters
00:04
Title
00:40
Measuring Depression at Baseline
02:31
Induction of Depression in Rats
04:03
Establishing Depression-contagion in Naïve Rats
04:37
Open Field Test
05:08
Forced-swim Test
05:50
Results: Sucrose Preference, Open Field and Forced Swim Test Performance after Induction of Depression-like Behavior
07:22
Conclusion
Summary
Automatic Translation
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Automatic Translation
该协议描述了一种新的模型, 通过这种模式, 健康的大鼠可以在一定时间内收缩抑郁症, periodthrough 感染慢性不可预测的压力大鼠。
Tags
Depression
Contagion
Rat Model
Behavioral Field
Mechanism
Prevention
Containment
Treatment
Therapy
Sucrose Preference Test
Chronic Unpredictable Stress
Housing
Food Deprivation
Water Deprivation
Wet Bedding
Continuous Lighting
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