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JoVE Journal Cancer Research
A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model
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A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model

Article DOI: 10.3791/57182-v • 08:14 min • February 28th, 2018
February 28th, 2018 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2
1Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, University of Utah, 2Huntsman Cancer Institute, University of Utah

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Summary
Automatic Translation

Environmental Enrichment (EE) is an animal housing environment that is used to reveal mechanisms that underlie the connections between lifestyle, stress, and disease. This protocol describes a procedure that uses a mouse model of colon tumorigenesis and EE to specifically define alterations in microbiota biodiversity that may impact animal mortality.

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Environmental Enrichment Colon Microbiome Biodiversity Mouse Colon Tumor Model Experimental Reproducibility Animal Stress Reduction Enriched Environment Etiology Of Disease Sterile Conditions Conventional Cages Nesting Material Sterilized Platform Running Wheels Tunnels Igloos Crawl Balls Ventilation
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