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JoVE Journal
Biology

This content is Open Access.

Miniaturized Sample Preparation for Transmission Electron Microscopy
 

Miniaturized Sample Preparation for Transmission Electron Microscopy

Article doi: 10.3791/57310
July 27th, 2018

Summary July 27th, 2018

An instrument and methods for the preparation of nanoliter-sized sample volumes for transmission electron microscopy is presented. No paper-blotting steps are required, thus avoiding the detrimental consequences this can have for proteins, significantly reducing sample loss and enabling the analysis of single cell lysate for visual proteomics.

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