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Journal
/
Neuroscience
/
微电极阵列技术在完整仔猪脑麻醉诱导神经毒性研究中的应用
JoVE Journal
Neuroscience
This content is Free Access.
JoVE Journal
Neuroscience
Adaptation of Microelectrode Array Technology for the Study of Anesthesia-induced Neurotoxicity in the Intact Piglet Brain
Please note that all translations are automatically generated.
Click here for the English version.
微电极阵列技术在完整仔猪脑麻醉诱导神经毒性研究中的应用
DOI:
10.3791/57391-v
•
08:23 min
•
May 12, 2018
•
Emily D. Geyer*
1
,
Prithvi A. Shetty*
1
,
Christopher J. Suozzi*
1
,
David Z. Allen*
1,2
,
Pamela P. Benavidez*
1,2
,
Joseph Liu*
1,3
,
Charles N. Hollis
,
Greg A. Gerhardt
,
Jorge E. Quintero
,
Jason J. Burmeister
,
Emmett E. Whitaker
3
1
Department of Anesthesiology
,
Ohio State University College of Medicine
,
2
Medical Student Research Program
,
Ohio State University College of Medicine
,
3
Department of Anesthesiology and Pain Medicine
,
Nationwide Children’s Hospital
,
4
Department of Neuroscience
,
University of Kentucky Medical Center
Chapters
00:04
Title
01:19
Set Up for Surgery
03:38
Microelectrode Array Placement
06:19
Results:
In Vivo
Glutamate Measurements from the Piglet Hippocampus
07:56
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
本研究探讨了用酶基微电极阵列技术监测仔猪
体内的活体
神经递质活性的新方法
.
假设谷氨酸失调有助于麻醉神经毒性的机制。在此, 我们提出了一种适应多边环境技术的协议, 研究麻醉诱发神经毒性的机制。
Tags
Microelectrode Array
Neurotransmitters
Anesthesia-induced Neurotoxicity
Piglet Brain
In Vivo Glutamate Activity
Pediatric Brain Trauma
Epilepsy
Stroke
Piglet Model
Sevoflurane Anesthesia
Stereotaxic Frame
Rocuronium
Vital Signs Monitoring
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