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JoVE Journal
Cancer Research

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Modeling osteosarkom ved hjælp af Li-Fraumeni syndrom Patient-afledte inducerede pluripotente stamceller-celler
 
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Modeling osteosarkom ved hjælp af Li-Fraumeni syndrom Patient-afledte inducerede pluripotente stamceller-celler

Article DOI: 10.3791/57664-v 08:52 min June 13th, 2018
June 13th, 2018

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Summary

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Click here for the English version.

Her præsenterer vi en protokol for generation af induceret pluripotente stamceller (iPSCs) fra Li-Fraumeni syndrom (LFS) patient afledte fibroblaster, differentiering af iPSCs via mesenchymale stamceller (msc) til osteoblaster og modellering in vivo tumordannelse med LFS patient-afledte osteoblaster.

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Kræftforskning sag 136 iPSCs Li-Fraumeni syndrom omprogrammering differentiering mesenkymale stamceller osteoblaster osteosarkom xenograft
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