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Journal / Bioengineering / 纳米传感器检测体内蛋白酶活性的无创诊断…
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Bioengineering

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JoVE Journal Bioengineering
纳米传感器检测体内蛋白酶活性的无创诊断
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纳米传感器检测体内蛋白酶活性的无创诊断

Article DOI: 10.3791/57937-v • 10:50 min • July 16th, 2018
July 16th, 2018 •
1, 1, 1,2,3,4,5
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech College of Engineering and Emory School of Medicine, 2Parker H. Petit Institute of Bioengineering and Bioscience, 3Institute for Electronics and Nanotechnology, Georgia Tech, 4Integrated Cancer Research Center, Georgia Tech, 5The Georgia Immunoengineering Consortium, Emory University and Georgia Tech

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蛋白酶是严格调控的酶参与基本的生物学过程, 失调蛋白酶活动推动复杂疾病, 如癌症的进展。该方法的目的是创造纳米传感器, 以测量体内蛋白酶的活动, 产生一个可从宿主尿和歧视性疾病检测到的裂解信号。

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生物工程 137 期 合成生物标志物 活性探针 蛋白酶 纳米传感器 纳米粒子 尿液诊断
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