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Bioengineering
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脊髓损伤后压力溃疡的小鼠模型
JoVE Journal
Bioengineering
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JoVE Journal
Bioengineering
Mouse Model of Pressure Ulcers After Spinal Cord Injury
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脊髓损伤后压力溃疡的小鼠模型
DOI:
10.3791/58188-v
•
06:51 min
•
March 09, 2019
•
Suneel Kumar
,
Yuying Tan
,
Martin L. Yarmush
2
,
Biraja C. Dash
,
Henry C. Hsia
,
Francois Berthiaume
1
Department of Biomedical Engineering
,
Rutgers University
,
2
Center for Engineering in Medicine
,
Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children
,
3
Department of Surgery
,
Yale School of Medicine, Yale University
Chapters
00:04
Title
00:35
T9-T10 Spinal Laminectomy
02:22
T9-T10 Complete Spinal Injury
03:11
Induction of Skin Pressure Ulcer after Complete SCI
04:22
Post-operative Animal Care, Euthanasia, and Tissue Collection for Histology
05:07
Results: Skin Wound Histology and Impact on Healing
06:15
Conclusion
Summary
Automatic Translation
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Automatic Translation
在这里, 我们描述了一个简单的方法, 以诱导临床相关的皮肤压疮 (pu) 在小鼠模型的脊髓损伤 (sci)。该模型可用于临床前的研究, 筛选不同的治疗方法治疗 pu 在 sci 患者。
Tags
Mouse Model
Pressure Ulcers
Spinal Cord Injury
Wound Healing
Laminectomy
SCI Surgery
Transection
Analgesia
Betadine
Depilatory Cream
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