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Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
JoVE Journal
Medicine
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JoVE Journal Medicine
Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
DOI:

05:48 min

September 26, 2019

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Chapters

  • 00:04Title
  • 00:48Lung Exsanguination
  • 02:02Lung Tissue Fixation
  • 03:38Results: Representative Mouse Lung Histologic and Morphometric Findings
  • 04:58Conclusion

Summary

Automatic Translation

Presented here is a useful protocol for lung fixation that creates a stable condition for histological evaluate of lung specimens from a mouse model of emphysema. The main advantage of this model is that it can fix many lungs with the same constant pressure without lung collapse or deflation.

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