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Chapters
- 00:04Title
- 00:47Arginine Glycine Aspartate (RGD)-Peptide Radiolabeling
- 02:42In Vitro Cellular Uptake and Serum Stability
- 04:17Lipophilicity Determination, Tumor Model Preparation, In Vivo Quantification, and Ex Vivo Biodistribution
- 06:05Results: Representative 68Ga-RGD-peptide Purification, Radiochemical Purity, and In Vivo Imaging and Ex Vivo Biodistribution Analyses
- 07:04Conclusion
The αvβ3 integrin is a type of adhesion protein that is highly expressed on activated endothelial cells undergoing angiogenesis. Thus, evaluating the integrity of the integrin is of great interest in oncology. Here, we introduce a method to prepare 68Ga-labeled radiopeptides and a method to assess its biological effectiveness.
