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Induktion av aterosklerotiska plack genom aktivering av mineralkortikoida receptorer i Apolipoprotein E-brist möss
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Induktion av aterosklerotiska plack genom aktivering av mineralkortikoida receptorer i Apolipoprotein E-brist möss

Article DOI: 10.3791/58303-v • 07:36 min • September 26th, 2018
September 26th, 2018 •
1, 1, 1, 1, 1,2
1Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele Pisana, Rome, Italy, 2Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Rome, Italy

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Vi beskriver ett protokoll för att framkalla åderförkalkning i aortaroten av ApoE- / - möss som utfodrats med en aterogena diet, genom en kontinuerlig frisättning av aldosteron. Metoder för att karakterisera plack sammansättning beskrivs också.

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Medicin fråga 139 åderförkalkning aldosteron inflammation ApoE- / - aortaroten immunohistokemi
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