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颅内药物治疗和啮齿动物疼痛检测
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Neuroscience
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JoVE Journal Neuroscience
Intracranial Pharmacotherapy and Pain Assays in Rodents
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颅内药物治疗和啮齿动物疼痛检测

DOI:
10.3791/58473-v

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02:26 min

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April 09, 2019

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, ,
1Department of Anesthesiology, Perioperative Care and Pain Medicine,New York University School of Medicine, 2Department of Neuroscience and Physiology,New York University School of Medicine

Chapters

  • 00:04Title
  • 00:20Study Drug Injection and Analgesia Response Analysis
  • 01:30Results: Intracranial AMPAkine Injection and Systemic Morphine Injection Provide Complementary Analgesia
  • 01:55Conclusion

Summary

Automatic Translation

Automatic Translation

在这里, 我们提出了一个方案, 以执行颅内药理实验, 其次是在啮齿类动物的疼痛行为检测。该协议允许研究人员在大脑中提供分子和细胞靶标, 用于治疗疼痛的药理剂。

Tags

Intracranial PharmacotherapyPain AssaysRodentsHargreaves ApparatusIntracranial InjectionsAMPAkineMorphineCentral Mechanisms Of PainBrain RegionPain Modulation

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