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联合遗传和化学衣壳改性腺病毒基因转移载体用于屏蔽和靶向
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Biology
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JoVE Journal
Biology
Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
Please note that all translations are automatically generated.
Click here for the English version.
联合遗传和化学衣壳改性腺病毒基因转移载体用于屏蔽和靶向
DOI:
10.3791/58480-v
•
08:14 min
•
October 26, 2018
•
Franziska Jönsson
,
Claudia Hagedorn
,
Florian Kreppel
1
Center of Biomedical Education and Research
,
University Witten/Herdecke
Chapters
00:04
Title
01:31
Coupling Moieties: Storage and Preparation
02:43
Amplification, Purification, and Chemical Modification of Ad Vectors
06:36
Results: Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors
07:14
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
本文所述的协议使研究人员能够通过简单的化学方法在选定的地点专门修改腺病毒衣壳。可生成屏蔽腺病毒载体颗粒和重定目标基因转移载体, 并可研究载体宿主相互作用。
Tags
Gene Therapy
Oncolysis
Genetic Vaccination
Adenovirus
Gene Transfer Vector
Capsid Modification
Chemical Modification
Vector-host Interaction
Virus Labeling
Virus Tracking
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