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左肺切除术联合单氯联氨酸或苏根为大鼠肺动脉高压的模型

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JoVE Journal Medicine

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Please note that all translations are automatically generated. Click here for the English version.

左肺切除术联合单氯联氨酸或苏根为大鼠肺动脉高压的模型

DOI:

10.3791/59050-v

•

07:29 min

•

March 08, 2019

•

Michael G. Katz, Anthony S. Fargnoli, Sarah M. Gubara, Malik Bisserier, Yassine Sassi, Charles R. Bridges, Roger J. Hajjar, Lahouaria Hadri

¹Cardiovascular Research Center, Department of Cardiology,Icahn School of Medicine at Mount Sinai

Chapters

00:04Title
01:06Rat Intubation and Sterile Environment Preparation
02:23Left Pneumonectomy
04:34Ribs and Intercostal Muscle Closure
05:37Results: Representative Pulmonary Hypertension in Rats
06:40Conclusion

Summary

Automatic Translation

啮齿类动物左肺切除术是肺动脉高压研究中的一项有价值的技术。在这里, 我们提出了一个协议来描述大鼠肺切除术程序和术后护理, 以确保最低的发病率和死亡率。

Tags

Keywords: Pulmonary Arterial Hypertension Pneumonectomy Monocrotaline Sugen Rat Model Endothelial Damage Regenerative Medicine Congenital Heart Defects Post-pneumonectomy Anesthesia Intubation Thoracotomy Lung Resection Surgical Technique

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