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Journal
/
Immunology and Infection
/
利用无脊椎
杆菌
作为感染模型研究
结核分枝杆菌
复合物
JoVE Journal
Immunology and Infection
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JoVE Journal
Immunology and Infection
Use of the Invertebrate
Galleria mellonella
as an Infection Model to Study the
Mycobacterium tuberculosis
Complex
Please note that all translations are automatically generated.
Click here for the English version.
利用无脊椎
杆菌
作为感染模型研究
结核分枝杆菌
复合物
DOI:
10.3791/59703-v
•
09:23 min
•
June 30, 2019
•
Masanori Asai*
1
,
Yanwen Li*
1
,
Jasmeet Singh Khara
2
,
Camilla A. Gladstone
,
Brian D. Robertson
,
Paul R. Langford*
1
,
Sandra M. Newton*
1
1
Section of Pediatric Infectious Diseases and Allergy, Department of Medicine
,
Imperial College London
,
2
Department of Pharmacy
,
National University of Singapore
,
3
MRC Centre for Molecular Bacteriology and Infection, Department of Medicine
,
Imperial College London
Chapters
00:04
Title
00:59
Preparation of
M. bovis
BCG
lux
for Infection
03:09
Infecting
G. mellonella
with BCG
lux
05:23
Measuring the In Vivo Burden of BCG
lux
in
G. mellonella
07:10
Results: BCG
lux
Dose Dependent Virulence
08:31
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
最近,肺
结核分枝杆菌
的可重复、廉价和合乎道德的感染模型被确立为一种可重复、廉价和合乎道德的感染模式。在这里,我们描述和演示了为成功感染生物发光
分枝杆菌BCG
lux
而采取的措施。
Tags
Galleria Mellonella
Tuberculosis
Infection Model
Mycobacterium
Innate Immunity
Alternative To Mammalian Models
Bioluminescence
BCG
Cell Culture
Sample Preparation
Article
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