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Anvendelse af viral Entry assays og molekylær docking-analyse til identifikation af antivirale kandidater mod coxsackievirus A16
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Immunology and Infection
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JoVE Journal Immunology and Infection
Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16

Anvendelse af viral Entry assays og molekylær docking-analyse til identifikation af antivirale kandidater mod coxsackievirus A16

DOI:
10.3791/59920-v

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06:03 min

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July 15, 2019

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, , ,
1Department of Molecular Biosciences,University of Texas at Austin, 2School of Pharmacy, College of Pharmacy,Kaohsiung Medical University, 3Graduate Institute of Medical Sciences, College of Medicine,Taipei Medical University, 4Department of Microbiology and Immunology,Dalhousie University, 5Department of Microbiology and Immunology, School of Medicine, College of Medicine,Taipei Medical University

Chapters

  • 00:04Title
  • 00:27Time-of-Drug-Addition
  • 02:25Molecular Docking Analysis
  • 04:06Results: Representative Effects of Small Molecule (CHLA and PUG) Binding Against CVA16 Infectivity
  • 05:33Conclusion

Summary

Automatic Translation

Automatic Translation

Målet med protokollen er at illustrere de forskellige assays vedrørende viral Entry, der kan anvendes til at identificere de ansøske virale indgangs hæmmere.

Tags

Viral Entry AssayMolecular DockingAntiviral CandidatesCoxsackievirus A16RD CellsPlaque-forming UnitsMethylcelluloseCrystal VioletPubChemProtein Data BankMolecular ProgramBio-computing Program

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