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创伤性脑损伤诱导受控皮质冲击的母模型

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury

Please note that all translations are automatically generated. Click here for the English version.

创伤性脑损伤诱导受控皮质冲击的母模型

DOI:

10.3791/60027-v

•

05:01 min

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August 16, 2019

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Steven J Schwulst, Mecca B.A.R. Islam

¹Department of Surgery,Northwestern University

Chapters

00:04Title
00:42Pre-Surgical Preparation
01:24Controlled Cortical Traumatic Brain Injury (TBI) Induction
03:02Surgical Site Closure and Post-Operative Care
03:39Results: Representative Gross, Histologic, and MRI Evaluation of Mouse Brain Tissue After Severe TBI
04:16Conclusion

Summary

Automatic Translation

在这里，我们描述了通过开头控制皮质撞击诱导鼠外创伤性脑损伤的协议。

Tags

Murine Model Controlled Cortical Impact Traumatic Brain Injury Stereotaxic Frame Craniectomy Dura Mater Impactor Tip Biomechanical Parameters Reproducible Injury

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