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研究左心室反向改造由主动脉脱体在啮齿动物
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JoVE Journal Medicine
Studying Left Ventricular Reverse Remodeling by Aortic Debanding in Rodents
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研究左心室反向改造由主动脉脱体在啮齿动物

DOI:
10.3791/60036-v

•

07:26 min

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July 14, 2021

•

, , ,
1Unidade de Investigação Cardiovascular, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina,Universidade do Porto

Chapters

  • 00:04Introduction
  • 01:07Aortic Banding Preparation and Post-Operative Care
  • 02:40Aortic Debanding
  • 03:36Echocardiography (ECG)
  • 05:26Results: Representative Echocardiographic, Pressure Volume, and Histological Assessments of Cardiac Structure and Function
  • 06:38Conclusion

Summary

Automatic Translation

Automatic Translation

在这里，我们描述了在成熟的主动脉收缩模型中手术主动脉脱体的分步协议。这个过程不仅允许研究左心室反向改造和肥大回归背后的机制，而且还可以测试可能加速心肌恢复的新疗法方案。

Tags

Left Ventricular Reverse RemodelingAortic DebandingRodentsMyocardial Reverse RemodelingCardiomyocytes RegressionIsometric Functional RecoveryPressure OverloadAortic StenosisMechanical VentilationAnalgesiaAortic BandingAortic Debanding

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