A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:04Introduction
- 01:07Aortic Banding Preparation and Post-Operative Care
- 02:40Aortic Debanding
- 03:36Echocardiography (ECG)
- 05:26Results: Representative Echocardiographic, Pressure Volume, and Histological Assessments of Cardiac Structure and Function
- 06:38Conclusion
Her beskriver vi en trinvis protokol af kirurgisk aorta debanding i den veletablerede mus model af aorta-indsnævring. Denne procedure ikke kun tillader at studere de mekanismer, der ligger til grund for venstre ventrikel omvendt remodeling og regression af hypertrofi, men også at teste nye terapeutiske muligheder, der kan fremskynde myokardie opsving.
