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Knoglemarvstransplantation platform til at undersøge den rolle, dendritiske celler i Graft-versus-Host Sygdom
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1Cancer Division, Burnett School of Biomedical Sciences,University of Central Florida, 2Department of Biochemistry,Hanoi University of Pharmacy, 3Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences,Houston Methodist Research Institute, 4Department of Epidemiology,University of Pittsburgh Graduate School of Public Health, 5Division of Cancer Control and Population Sciences,University of Pittsburgh Medical Center, Hillman Cancer Center
Chapters
- 00:04Introduction
- 00:49Graft-Versus-Host Disease (GVHD) Induction
- 02:53Donor T Cell Preparation
- 04:54Bone Marrow-Derived Dendritic Cell (BM-DC) Preparation
- 05:58Results: Representative Effects of Dendritic Cell Function in GVHD
- 07:26Conclusion
Graft-versus-host sygdom er en stor komplikation efter allogen knoglemarvstransplantation. Dendritiske celler spiller en afgørende rolle i patogenesen af graft-versus-host sygdom. Den nuværende artikel beskriver en ny knoglemarvstransplantation platform til at undersøge den rolle, dendritiske celler i udviklingen af graft-versus-host sygdom og graft-versus-leukæmi effekt.
