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Etablering af en svin model af post-myokardieinfark hjertesvigt for stamcellebehandling
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JoVE Journal Medicine
Establishing a Swine Model of Post-myocardial Infarction Heart Failure for Stem Cell Treatment

Etablering af en svin model af post-myokardieinfark hjertesvigt for stamcellebehandling

DOI:
10.3791/60392-v

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08:24 min

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May 25, 2020

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, , , , ,
1Cardiology Division, Department of Medicine, Queen Mary Hospital,University of Hong Kong, 2Shenzhen Institutes of Research and Innovation,University of Hong Kong

Chapters

  • 00:04Introduction
  • 00:46Pacemaker Implantation
  • 01:39Invasive Pressure Volume Loop Analysis
  • 02:55Myocardial Infarction (MI) Induction
  • 04:03Stem Cell Injection
  • 05:02Intracardiac Programmed Electrical Stimulation
  • 06:01Results: Representative Cardiac Function, Morphology, Cell Survival, and Inducible Ventricular Arrhythmia
  • 07:41Conclusion

Summary

Automatic Translation

Automatic Translation

Vi forsøgte at etablere en svinemodel af hjertesvigt forårsaget af venstre circumflex arterie blokering og hurtig pacing at teste effekten og sikkerheden af intramyocardial administration af stamceller til celle-baserede behandlinger.

Tags

Swine ModelPost-myocardial InfarctionHeart FailureStem Cell TreatmentLeft Circumflex Artery BlockageRapid PacingInfarct SizeLeft Ventricle InjectionRight Carotid ArteryJugular VeinPacemakerRight Femoral ArteryFemoral VeinPressure Volume CatheterMyocardial InfarctionVentricular ArrhythmiasAmiodaroneLidocaineCoronary Angiography

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