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Kemisk-inducerad hud carcinogenes modell med Dimetylbenz [a] antracen och 12-O-Tetradecanoyl Phorbol-13-acetat (DMBA-TPA)
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA)
DOI:

04:12 min

December 19, 2019

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Chapters

  • 00:05Title
  • 00:56Skin Papilloma Induction and Promotion
  • 02:00Sample Collection
  • 02:43Results: Representative Outcomes and Histological Analyses in the DMBA-TPA Model
  • 03:12Conclusion

Summary

Automatic Translation

Två-stegs hud cancerogenesen induceras av två topikalt applicerade kemikalier. En mutagen 7, 12-dimetylbenz [a] antracen) orsakar mutationer i epidermala celler och en kontinuerlig tillämpning av allmän tillväxt stimulator 12-O-tetradecanoyl phorbol-13-acetat accelererar hudpapillom formation.

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