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Inducerende akut leverskade hos rotter via tetrachlormethan (CCl4)Eksponering gennem et orogastrisk rør
 
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Inducerende akut leverskade hos rotter via tetrachlormethan (CCl4)Eksponering gennem et orogastrisk rør

Article DOI: 10.3791/60695-v
April 28th, 2020

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Summary April 28th, 2020

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Denne protokol beskriver en fælles og gennemførlig metode til at fremkalde akut leverskade (ALI) via CCl4 eksponering gennem et orogastrisk rør. Cl4 eksponering inducerer ALI gennem dannelsen af reaktive ilt arter under sin biotransformation i leveren. Denne metode bruges til at analysere patofysiologi af ALI og undersøge forskellige hepatoprotective strategier.

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