/

/

Fabrication of Ti₃C₂ MXene Microelectrode Arrays for In Vivo Neural Recording

JoVE Journal
Bioengineering

A subscription to JoVE is required to view this content. Sign in or start your free trial.

JoVE Journal Bioengineering

Fabrication of Ti₃C₂ MXene Microelectrode Arrays for In Vivo Neural Recording

Fabrication of Ti₃C₂ MXene Microelectrode Arrays for In Vivo Neural Recording

DOI:

10.3791/60741-v

•

09:58 min

•

February 12, 2020

•

Nicolette Driscoll^2,3, Kathleen Maleski⁵, Andrew G. Richardson⁶, Brendan Murphy^2,3, Babak Anasori⁵, Timothy H. Lucas⁶, Yury Gogotsi⁵, Flavia Vitale^2,3,7,8

¹Department of Bioengineering,University of Pennsylvania, ²Center for Neuroengineering and Therapeutics,University of Pennsylvania, ³Corporal Michael J. Crescenz Veterans Affairs Medical Center, ⁴Department of Materials Science and Engineering,Drexel University, ⁵A.J. Drexel Nanomaterials Institute,Drexel University, ⁶Department of Neurosurgery,University of Pennsylvania, ⁷Department of Neurology,University of Pennsylvania, ⁸Department of Physical Medicine and Rehabilitation

Chapters

00:05Introduction
00:27Titanium Carbide (Ti₃C₂) MXene Synthesis
02:59Ti₃C₂ MXene Microelectrode Array Fabrication
04:50Sacrificial Parylene-C Layer Deposition
05:54MXene Solution Spin Coating and Parylene-C Removal
08:22Results: Representative Neural Recording Results
09:24Conclusion

Summary

Automatic Translation

We describe here a method for fabricating Ti₃C₂ MXene microelectrode arrays and utilizing them for in vivo neural recording.

Tags

Keywords: Ti3C2 MXene Microelectrode Array Neural Recording Metallic Conductivity Micropatterning Titanium Aluminum Carbide Etching Intercalation Delamination Size Selection

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

Fabrication of Micropatterned Hydrogels for Neural Culture Systems using Dynamic Mask Projection Photolithography

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules

Adaptation of a Haptic Robot in a 3T fMRI

High efficiency, Site-specific Transfection of Adherent Cells with siRNA Using Microelectrode Arrays (MEA)

Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.

Sealable Femtoliter Chamber Arrays for Cell-free Biology

Easy and Accurate Mechano-profiling on Micropost Arrays

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography

Interfacing Microfluidics with Microelectrode Arrays for Studying Neuronal Communication and Axonal Signal Propagation

Read Article