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November 17, 2015
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Described are protocols for quantifying mechanical interactions between adherent cells and microstructured substrates. These interactions are closely linked to essential cell behaviors including migration, proliferation, differentiation, and apoptosis. The protocols present an open-source image analysis software called MechProfiler, which enables determination of involved forces for each micropost.
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Cite this Article
Goedecke, N., Bollhalder, M., Bernet, R., Silvan, U., Snedeker, J. Easy and Accurate Mechano-profiling on Micropost Arrays. J. Vis. Exp. (105), e53350, doi:10.3791/53350 (2015).
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