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Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat
JoVE Journal
Medicine
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JoVE Journal Medicine
Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat
DOI:

14:18 min

August 30, 2020

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Chapters

  • 00:00Introduction
  • 01:24Protocol
  • 12:47Results
  • 13:30Conclusion

Summary

Automatic Translation

This protocol presents a robust, reproducible model of vascularized composite allotransplant (VCA) geared toward simultaneous study of immunology and functional recovery. The time invested in meticulous technique in a right mid-thigh hind limb orthotopic transplant with hand sewn vascular anastomoses and neural coaptation yields the ability to study functional recovery.

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