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Journal / Biochemistry / Caracterização de estruturas amilóides em…
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Biochemistry

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JoVE Journal Biochemistry
Caracterização de estruturas amilóides em Envelhecimento C. Elegans usando imagem de fluorescência ao longo da vida
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Caracterização de estruturas amilóides em Envelhecimento C. Elegans usando imagem de fluorescência ao longo da vida

Article DOI: 10.3791/61004-v • 09:31 min • March 27th, 2020
March 27th, 2020 •
*1,2, *1, *1, 3, 1,4
1Leibniz Research Institute for Molecular Pharmacology im Forschungsverbund Berlin, 2NeuroCure Cluster of Excellence, Charité - Universitätsmedizin Berlin, 3Molecular Neuroscience Group, Department of Chemical Engineering and Biotechnology, University of Cambridge, 4Cell Biology, University of Bremen
* These authors contributed equally

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A fluorescência de imagens ao longo da vida monitora, quantifica e distingue as tendências de agregação de proteínas em modelos de doença susturais de C. elegans vivos, envelhecidos e estressados.

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Bioquímica Edição 157 C. elegans,agregação envelhecimento rede de proteotase knockdown de siRNA microscopia de imagem de vida de fluorescência (FLIM) contagem de fótons únicos correlacionados pelo tempo (TCSPC) vida útil (tau)
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