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Bioengineering

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JoVE Journal Bioengineering
Préparation des microenvironnements de matrice extracellulaire tunable pour évaluer les spécifications du phénotype de cellules de Schwann
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Préparation des microenvironnements de matrice extracellulaire tunable pour évaluer les spécifications du phénotype de cellules de Schwann

Article DOI: 10.3791/61496-v • 07:50 min • June 2nd, 2020
June 2nd, 2020 •
1, 1, 1,2,3
1Department of Chemical and Environmental Engineering, University of Cincinnati, 2Department of Biomedical Engineering, University of Cincinnati, 3Neuroscience Graduate Program, University of Cincinnati College of Medicine

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Cette méthodologie vise à illustrer les mécanismes par lesquels les signaux de matrice extracellulaire tels que la rigidité du substrat, la composition des protéines et la morphologie cellulaire régulent le phénotype des cellules Schwann (SC).

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Ce mois-ci dans JoVE Numéro 160 Cellules Schwann nerf périphérique rigidité de matrice matrice extracellulaire micropatternage phénotype cellulaire plasticité forme cellulaire
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