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1Department of Dental Materials and Prosthodontics, School of Dentistry,São Paulo State University (UNESP), 2Department of Organic Chemistry, Institute of Chemistry,São Paulo State University (UNESP), 3Faculty of Pharmaceutical Sciences of Ribeiraão Preto (FCFRP-USP), Department of Physics and Chemistry,University of São Paulo
Chapters
- 00:04Introduction
- 00:53Preparation of Crude Extracts (CE) and Fractions (CEF) to Chemical Profile Analysis and Bioassays
- 02:26Bioassay and Anti-microbial Activity
- 04:10Validation of Biological Activity and Biological Data Analysis
- 06:16Results: The Screening Results of the Twelve Crude Extracts from Three Varieties of C. sylvestris Against S. mutans
- 07:31Conclusion
Naturlige produkter representerer lovende utgangspunkt for utvikling av nye legemidler og terapeutiske midler. Men på grunn av det høye kjemiske mangfoldet er det utfordrende og tidkrevende å finne nye terapeutiske forbindelser fra planter. Vi beskriver en forenklet tilnærming for å identifisere antimikrobielle og antibiofilmmolekyler fra planteekstrakter og fraksjoner.
