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Journal / Genetics / Prøveforberedelse til bioinformatik Analyse af…
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Genetics
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JoVE Journal Genetics
Prøveforberedelse til bioinformatik Analyse af DNA-methylering
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Prøveforberedelse til bioinformatik Analyse af DNA-methylering: Foreningsstrategi for fedme og relaterede trækundersøgelser

Article DOI: 10.3791/62598-v • 14:56 min • May 6th, 2022
May 6th, 2022 •
*1, *1, 1, 2,3, 1, 4, 5, 1, 1, 6, 7, 8, 9, 6
1Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, 2Centre for Computational Biology, University of Birmingham, 3Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, 4Cancer Genetics and Evolution Laboratory, Cancer Research UK, Institute of Genetics & Molecular Medicine, The University of Edinburgh, 5Ribeirão Preto School of Physical Education and Sport, University of São Paulo, 6Health Sciences Department, Ribeirao Preto Medical School, University of Sao Paulo, 7Faculty of Pharmaceutical Sciences, University of São Paulo, 8Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, 9Department of Clinical, Bromatological and Toxicological Analysis, Faculty of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo
* These authors contributed equally

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Den foreliggende undersøgelse beskriver arbejdsgangen til styring af DNA-methyleringsdata opnået ved hjælp af mikroarray-teknologier. Protokollen demonstrerer trin fra prøveforberedelse til dataanalyse. Alle procedurer er beskrevet detaljeret, og videoen viser de væsentlige trin.

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Genetik udgave 183 DNA-methylering fedme ChAMP bioinformatik epigenetik fedtmasse body mass index
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