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Journal / Genetics / DNA甲基化生物信息学分析的样品制备：肥胖和相关性状研究的关联策略…
JoVE Journal
Genetics
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JoVE Journal Genetics
DNA甲基化生物信息学分析的样品制备：肥胖和相关性状研究的关联策略
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DNA甲基化生物信息学分析的样品制备：肥胖和相关性状研究的关联策略

Article DOI: 10.3791/62598-v • 14:56 min • May 6th, 2022
May 6th, 2022 •
*1, *1, 1, 2,3, 1, 4, 5, 1, 1, 6, 7, 8, 9, 6
1Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, 2Centre for Computational Biology, University of Birmingham, 3Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, 4Cancer Genetics and Evolution Laboratory, Cancer Research UK, Institute of Genetics & Molecular Medicine, The University of Edinburgh, 5Ribeirão Preto School of Physical Education and Sport, University of São Paulo, 6Health Sciences Department, Ribeirao Preto Medical School, University of Sao Paulo, 7Faculty of Pharmaceutical Sciences, University of São Paulo, 8Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, 9Department of Clinical, Bromatological and Toxicological Analysis, Faculty of Pharmaceutical Sciences of Ribeirao Preto, University of São Paulo
* These authors contributed equally

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本研究描述了管理通过微阵列技术获得的DNA甲基化数据的工作流程。该协议演示了从样品制备到数据分析的步骤。详细描述了所有程序，视频显示了重要的步骤。

Tags

遗传学，第183期，DNA甲基化，肥胖，ChAMP，生物信息学，表观遗传学，脂肪量，体重指数
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