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Immunology and Infection

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JoVE Journal Immunology and Infection
Sanntidsovervåking av mitokondrie respirasjon i cytokin-differensierte humane primære T-celler
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Sanntidsovervåking av mitokondrie respirasjon i cytokin-differensierte humane primære T-celler

Article DOI: 10.3791/62984-v • 06:55 min • October 19th, 2021
October 19th, 2021 •
*1, *1, 1, 1, 1,3, 2, 1
1National Center for Cancer Immune Therapy, Department of Oncology, University Hospital Herlev, 2Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, 3Department of Immunology and Microbiology, Inflammation and Cancer Group, University of Copenhagen
* These authors contributed equally

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Metabolsk tilpasning er grunnleggende for T-celler da det dikterer differensiering, utholdenhet og cytotoksisitet. Her presenteres en optimalisert protokoll for overvåking av mitokondrie-respirasjon i ex vivo cytokin-differensierte primære T-celler.

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