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JoVE Journal Neuroscience
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Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Article DOI: 10.3791/63085-v • 07:13 min • October 20th, 2021
October 20th, 2021 •
1,2, 1, 3,4, 1, 3,4, 3, 3,4, 3,4,5,6, 7, 8, 3,4,6,9,10,11,12, 1,3,13
1Laboratory of Regenerative Rehabilitation, Shirley Ryan AbilityLab, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, 2Northwestern University Interdepartmental Neuroscience Program, 3Center for Bio-integrated Electronics, Querrey Simpson Institute for Bioelectronics, Northwestern University, 4Department of Materials Science and Engineering, Northwestern University, 5Department of Civil and Environmental Engineering, Northwestern University, 6Department of Mechanical Engineering, Northwestern University, 7Arms and Hands Lab, Shirley Ryan AbilityLab, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, 8Division of Plastic and Reconstructive Surgery, Biologics, Shirley Ryan AbilityLab, Northwestern University, 9Department of Biomedical Engineering, Northwestern University, 10Department of Neurological Surgery, Northwestern University, 11Department of Chemistry, Northwestern University, 12Department of Electrical and Computer Engineering, Northwestern University, 13The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine

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Summary
Automatic Translation

This is a protocol for the surgical implantation and operation of a wirelessly powered interface for peripheral nerves. We demonstrate the utility of this approach with examples from nerve stimulators placed on either the rat sciatic or phrenic nerve.

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Implantation Control Wireless Battery-free Systems Peripheral Nerve Interfacing Sensors Actuators Tethered Systems Battery Power Operation Time Frame Developments Fully Implantable Devices Wired Precursors Surgical Implantation Wireless Power And Control Adult Rats Sciatic Nerve Model Phrenic Nerve Model Compound Muscle Action Potentials (CMAPs) Therapeutic Electrical Stimulation Protocol Conduit For Nerve Repair Expanded Treatment Options
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