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小鼠心肌梗死和心肌缺血再灌注损伤的诱导
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JoVE Journal Medicine
Induction of Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury in Mice
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小鼠心肌梗死和心肌缺血再灌注损伤的诱导

DOI:
10.3791/63257-v

•

08:28 min

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January 19, 2022

•

, , , , , , , , ,
1Department of Cardiology, Union Hospital, Tongji Medical College,Huazhong University of Science and Technology

Chapters

  • 00:04Introduction
  • 00:35Preoperative Preparation
  • 03:10Thoracotomy
  • 04:36LAD Ligation
  • 06:05Reperfusion
  • 07:13Results: A Simple and Reproductive Murine Model for Myocardial Ischemia-Reperfusion Injury and Myocardial Infarction
  • 07:48Conclusion

Summary

Automatic Translation

Automatic Translation

在这里，我们描述了一种简单且可重复的方法，该方法可以通过显微操作精确结扎左前降支冠状动脉来诱导小鼠心肌梗死或心肌缺血再灌注损伤。

Tags

Myocardial InfarctionMyocardial Ischemia-reperfusion InjuryMouse ModelLeft Anterior Descending Coronary Artery LigationSurgical ProcedureIntubationMechanical VentilationECG Monitoring

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