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Zebrafish Larvae as a Model to Evaluate Potential Radiosensitizers or Protectors
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Zebrafish Larvae as a Model to Evaluate Potential Radiosensitizers or Protectors
DOI:

04:53 min

August 25, 2022

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Chapters

  • 00:04Introduction
  • 00:57Monitoring Embryos and Selection for Radiation Experiments
  • 01:28X‐Ray Irradiation
  • 02:38Data Collection, Imaging, and Analysis
  • 03:17Results: Effect of Different Doses of X‐Ray Irradiation on 6 hpf Zebrafish Embryos
  • 04:23Conclusion

Summary

Automatic Translation

The zebrafish has recently been exploited as a model to validate potential radiation modifiers. The present protocol describes the detailed steps to use zebrafish embryos for radiation-based screening experiments and some observational approaches to evaluate the effect of different treatments and radiation.

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