JoVE Journal
Cancer Research
Cancer Research
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マウスにおける連続局所キメラ抗原受容体(CAR)T細胞注入のための頭蓋内カニューレ移植
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Article
DOI:
10.3791/64886-v
•
05:22 min
•
February 24th, 2023
マウスにおける連続局所キメラ抗原受容体(CAR)T細胞注入のための頭蓋内カニューレ移植
February 24th, 2023
•
Kyra Harvey1, Peter J. Madsen2,3, Tiffany Smith2, Crystal Griffin1,2, Luke Patterson1,2, Nicholas A. Vitanza4,5, Phillip B. Storm2,3, Adam C. Resnick2,3, Jessica B. Foster1,2
1Division of Oncology, Children’s Hospital of Philadelphia, 2Center for Data Driven Discovery in Biomedicine, Children’s Hospital of Philadelphia, 3Division of Neurosurgery, Children’s Hospital of Philadelphia, 4Ben Towne Center for Childhood Cancer Research, Seattle Children’s Research Institute, 5Department of Pediatrics, Seattle Children’s Hospital, University of Washington
Chapters
Summary
Please note that all translations are automatically generated.
Click here for the English version.
中枢神経系(CNS)腫瘍は、小児のがん関連死の主な原因であり、局所免疫ベースの治療法は、臨床試験で患者に対してますますテストされています。このプロトコルは、CNS腫瘍を標的とする免疫療法注入の前臨床評価のためのマウスへの局所カニューレ移植の方法を記載しています。