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Journal / Cancer Research / Implante de Cânula Intracraniana para Infusões…
JoVE Journal
Cancer Research

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JoVE Journal Cancer Research
Implante de Cânula Intracraniana para Infusões Seriadas de Células T com Receptor de Antígeno Quimérico Quimérico (CAR) em Camundongos
Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
Journal (Cancer Research)
Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue
Journal (Cancer Research)
Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue
 
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Implante de Cânula Intracraniana para Infusões Seriadas de Células T com Receptor de Antígeno Quimérico Quimérico (CAR) em Camundongos

Article DOI: 10.3791/64886-v • 05:22 min • February 24th, 2023
February 24th, 2023 •
1, 2,3, 2, 1,2, 1,2, 4,5, 2,3, 2,3, 1,2
1Division of Oncology, Children’s Hospital of Philadelphia, 2Center for Data Driven Discovery in Biomedicine, Children’s Hospital of Philadelphia, 3Division of Neurosurgery, Children’s Hospital of Philadelphia, 4Ben Towne Center for Childhood Cancer Research, Seattle Children’s Research Institute, 5Department of Pediatrics, Seattle Children’s Hospital, University of Washington

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Os tumores do sistema nervoso central (SNC) são a principal causa de morte relacionada ao câncer em crianças, e as terapias loco-regionais baseadas em imunidade estão sendo cada vez mais testadas para pacientes em ensaios clínicos. Este protocolo descreve métodos de implante de cânula locorregional em camundongos para avaliação pré-clínica de infusões imunoterápicas direcionadas a tumores do SNC.

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Este mês no JoVE edição 192
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