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Fabrication of Myogenic Engineered Tissue Constructs
JoVE Journal
Biology
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JoVE Journal Biology
Fabrication of Myogenic Engineered Tissue Constructs
DOI:

13:43 min

May 01, 2009

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Chapters

  • 00:00Title
  • 00:47Introduction
  • 01:23Assembly of Construct Casting Molds
  • 03:25Preparation for Myoblast Cell Isolation
  • 04:56Myoblast Isolation from Skeletal Muscle
  • 09:09Casting Engineered Tissue Constructs
  • 13:17Conclusion

Summary

Automatic Translation

Here, we demonstrate fabrication of collagen-based, tissue constructs containing skeletal myoblasts. These 3-D engineered constructs may be used to replace or repair tissues in vivo. For our purposes, we have designed these as an atrioventricular electrical conduit for the repair of complete heart block[1].

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