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Immunology and Infection

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JoVE Journal Immunology and Infection
In Vitro and In Vivo Model to Study Bacterial Adhesion to the Vessel Wall Under Flow Conditions
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In Vitro and In Vivo Model to Study Bacterial Adhesion to the Vessel Wall Under Flow Conditions

Article DOI: 10.3791/52862-v • 10:24 min • June 11th, 2015
June 11th, 2015 •
1, 1, 1, 1, 1, 1
1Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven

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Summary
Automatic Translation

To study the interaction of bacteria with the blood vessels under shear stress, a flow chamber and an in vivo mesenteric intravital microscopy model are described that allow to dissect the bacterial and host factors contributing to vascular adhesion.

Tags

In Vitro In Vivo Bacterial Adhesion Vessel Wall Flow Conditions Endovascular Infections Infective Endocarditis Shear Stress Flow Chamber Model Extracellular Matrix Endothelial Cells Intravital Microscopy Model Splanchnic Circulation Shear Stress Relevance Von Willebrand Factor Staphylococcus Aureus
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