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A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse
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A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse

A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse

DOI:
10.3791/54658-v

•

04:55 min

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November 17, 2016

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, , ,
1Department of Ophthalmology and Visual Sciences,University of Illinois at Chicago

Chapters

  • 00:05Title
  • 00:48Abrading the Corneal Epithelium
  • 03:17Results: Corneal Phenotype after Creating LSCD in Mice
  • 03:51Conclusion

Summary

Automatic Translation

Automatic Translation

The following article provides an easy, reproducible technique to effectively create a sustainable mouse model of limbal stem cell deficiency (LSCD). This animal model is useful in testing and comparing the efficacy of treatments for limbal stem cell diseases.

Tags

Limbal Stem Cell DeficiencyMouse ModelCorneal EpitheliumRotating BurrPovidone IodineTetracaine HydrochlorideErythromycin Ophthalmic OintmentFluorescein SodiumAnesthesiaSurgical MicroscopeCorneal Injury

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