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Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent
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Immunology and Infection
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JoVE Journal Immunology and Infection
Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent

DOI:
10.3791/55180-v

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06:46 min

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May 08, 2017

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, , , ,
1Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy,Eberhard Karls University of Tübingen, 2Department of Nuclear Medicine,Eberhard Karls University of Tübingen, 3Department of Dermatology,Eberhard Karls University of Tübingen

Chapters

  • 00:05Title
  • 00:42Rheumatoid Arthritis (RA) Induction and Chronic Hypersensitivity Reaction (CHR)
  • 02:10Optical Imaging (OI)
  • 04:01Results: Representative MMP OI in RA, CHR, and Control Animals
  • 05:35Conclusion

Summary

Automatic Translation

Automatic Translation

This paper explains the application of fluorescent imaging using an activatable optical imaging probe to visualize the in vivo activity of key matrix metalloproteinases in two different experimental models of inflammation.

Tags

In VivoFluorescenceOptical ImagingMatrix MetalloproteasesMMPActivatable ProbeInflammationRheumatoid ArthritisContact HypersensitivityTNCBTail Vein InjectionOptical Imaging Dye

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