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An Alternative Approach to Study Primary Events in Neurodegeneration Using Ex Vivo Rat Brain Slices
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
An Alternative Approach to Study Primary Events in Neurodegeneration Using Ex Vivo Rat Brain Slices
DOI:

07:57 min

April 11, 2018

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Chapters

  • 00:04Title
  • 00:58Preparations
  • 02:36Brain Extraction and Slicing
  • 04:33Tissue Section Treatment and Homogenization
  • 06:23Results: Neurodegenerative Effect of T30 on the Basal Forebrain
  • 07:41Conclusion

Summary

Automatic Translation

We present a method which can provide further insights into the early events underlying neurodegeneration and based on the established ex-vivo brain technique, combining the advantages of in vivo and in vitro experiments. Moreover, it represents a unique opportunity for direct comparison of treated and untreated group in the same anatomical plane.

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